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Article Type

Review

Abstract

A metabolic illness known as diabetes mellitus (DM) is brought on by the body's decreased secretion and/or activity of the hormone insulin. The condition worsens, pathological alterations in the body, such as nephropathy, retinopathy, and cardiovascular problems, become inevitable. Type I and II DM are the two primary subtypes of DM. Oral hypoglycaemics are used to treat type II diabetes, while insulin replacement therapy is typically used to treat type I diabetes. Patients typically receive dual drug treatments. Despite using oral hypoglycemic medications as monotherapy, have not been able to accomplish their therapeutic goals with first-line therapy.

In the current research, compiled the analytical methods reported for the estimation of some drugs diabetes in formulations for medicines. Most extensively used Technique like High-performance liquid chromatography (HPLC) was reported in Table1, 2,3,4 and 5. These Tables show an overview of the reported HPLC methods for drugs of diabetes in combination respectively indicating the HPLC conditions.

Keywords

Diabetes Mellitus (DM), High-Performance Liquid Chromatography (HPLC), Glimepiride (GLM), Metformin (MET), Glipizide (GLP), Acarbose (ACA), Glibenclamide (GLB), Repaglinide (REP)

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