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Article Type

Original Study

Abstract

Hepatocellular carcinoma (HCC) is the second most common cancer in humans and the fifth most prevalent worldwide. Although the survival rate of HCC has increased over time, postoperative recurrences remain high after a decade. HCC can be caused by both viral and non-viral diseases. There are two major global risk factors for HCC these are: hepatitis B virus (HBV) and hepatitis C virus (HCV). As part of routine health exams, complete blood counts can detect a variety of disorders, including infections, anemia, immune system disorders, and blood cancers. A complete blood count (CBC) can be used to perform a biochemical profile, which evaluates several critical organs and systems. Additionally, the CBC can detect red blood cell disorders, inflammation, and other metabolic disorders. The aim of this study is to identify the most significant and co-related haematological and biochemical parameters among patients with HCC, HBV, and HCV. The results revealed that some haematological and biochemical parameters changed significantly in the three groups (HCC, HBV, and HCV). Each liver disease can be evaluated using a single parameter, including the MPV for HCC, the MID for HBV, and the P-LCC for HCV. Despite this, two parameters are common to all three liver diseases, namely GOT (AST) and indirect bilirubin.

Keywords

Hepatocellular carcinoma, HBV, HCV, Hematology, Biochemistry

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