Immunological Markers and Clinical Features with Systemic Lupus Erythematosus in Iraqi Women Patients

Authors

Ali Yahya. Zeki, Medical Laboratory Technique, College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqFollow
Ali Hussein. Al-Hafid, Community Health Technique, College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq AND Rheumatology Unit, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq
Haider Hafudh Humaish, Medical Laboratory Technique, Kut Technical Institute, Middle Technical University, Wasit, Iraq

Article Type

Original Study

Abstract

Background: Systemic Lupus Erythematosus is a complicated condition caused by the immune system attacking disease with unclear causes, affecting mainly women. It manifests with various symptoms and is diagnosed based on clinical and serological signs. Aims: To investigate the prevalence and the type of immunological and hematologic manifestations in SLE from pathologist's perspective. Methods: The study was done on 60 SLE patients and 60 controls from the Consulting Rheumatology Clinic in Baghdad Teaching Hospital in Baghdad City during the first half of the year 2024, from 25^th January 2024 until 25^th April 2024. Results: Marital state that has married more affected (66.7%). 95% of patients tested positive for the anti-nuclear antibody and the anti dsDNA antibody also showed a high rate of positivity 86.7%. Hb and ESR highly significant difference (P=0.001) compared between patients and controls. The Arthralgia and arthritis were most common clinical features observed in SLEDAI and included (85%). Conclusions: Anti-dsDNA is a common antibody responsible for active diseases. Arthralgia and arthritis are most affected by SLE disease.

Keywords

SLE, Autoantibodies, Antinuclear antibodies, Indirect immunofluorescence

Recommended Citation

Zeki, Ali Yahya.; Al-Hafid, Ali Hussein.; and Humaish, Haider Hafudh (2024) "Immunological Markers and Clinical Features with Systemic Lupus Erythematosus in Iraqi Women Patients," Al-Esraa University College Journal for Medical Sciences: Vol. 5: Iss. 8, Article 4.
DOI: https://doi.org/10.70080/2790-7937.1036